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, B. Ed. , Ph. D. From financial literacy to financial well being; a studyof the level of financial literacy of women teaching facultyin educational institutions in Coimbatore regionDoctoral Dissertation . S.
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At the end of 18 weeks, the three groups of mice were killed, and the level of skin tumor formation was analyzed. Conney said mice in all three groups developed malignant skin tumors, called squamous cell carcinomas, but the number of tumors per mouse was reduced by 72 percent in those treated with caffeine and by 66 percent among those treated with EGCG, compared to the controls treated only with acetone. The treated mice also had fewer nonmalignant, sunlight related tumors, said Conney. Compared to the control group of mice, the mice treated with caffeine had 44 percent fewer nonmalignant tumors, the EGCG group 55 percent fewer, he said. Conney said that although both compounds were effective in lower tumor risk, caffeine has an advantage because it is chemically more stable than EGCG. Unlike sun screen lotions, which protect against skin cancer by preventing the skin from absorbing ultraviolet rays from the sun, the caffeine's cancer protection works in the cells after exposure to the ultraviolet rays. Rays from the sun can cause genetic changes in the skin that can lead to skin cancer. Conney said caffeine apparently blocks this action by causing abnormal cells to kill themselves, a type of programed cell suicide that prevents development of abnormal growths. "This is not a sunscreening effect," said Conney. "It is a biological effect. "He said the caffeine acts selectively, causing the abnormal cells to die but not affecting the normal cells.